Vitamin B12 and Iron Deficiency: Symptoms and How to Treat Them

  • Vitamin B12 is required for numerous cellular functions such as DNA synthesis and red blood cell production.
  • Iron is an essential mineral for making hemoglobin that is responsible for carrying oxygen around the body.
  • Vitamin B12 deficiency could also lead to Iron deficiency anemia.
Vitamin B12 and Iron Deficiency Symptoms and How to Treat Them

Vitamin B12 and Iron are vital nutrients that are crucial to preserving our general health and wellbeing. However, a lack of either of these nutrients can result in a variety of complications and health issues. Initial signs of iron and vitamin B12 deficiency can be subtle, making them simple to ignore. However, these deficiencies can lead to serious health problems like anemia, fatigue, weakness, and more if left untreated. This article will cover the warning signs and symptoms of vitamin B12 and iron deficiency as well as some efficient treatments. Continue reading to find out the significance of iron and vitamin B12, as well as how to make sure you are getting enough of them in your diet, whether you are experiencing symptoms or you simply want to learn more about these vital nutrients.

The Importance of Vitamin B12 and Iron in the Body

Vitamin B12 is required for numerous cellular functions, including DNA synthesis, red blood cell production, and normal nerve function. It can be found in animal products like meat, fish, and dairy as well as in supplement form.

Iron, on the other hand, is an essential mineral for making hemoglobin, the protein responsible for carrying oxygen around the body. Heme iron is best absorbed when consumed red meat, poultry, and fish; non-heme iron is best absorbed when consumed leafy greens, nuts, and beans. Foods derived from animals and plants both contain iron.

Iron and vitamin B12 are both essential to good health and their deficiency can have serious consequences.

Symptoms of Vitamin B12 Deficiency

Lack of vitamin B12 is a common issue, particularly in vegetarians and older people. It is simple to ignore the subtle early signs of a vitamin B12 deficiency. However, the symptoms could get worse as the deficiency gets worse. Common signs of a vitamin B12 deficiency include the following:

  • Fatigue and weakness
  • Numbness or tingling in the hands and feet
  • Difficulty walking or maintaining balance
  • Mood changes, such as depression or irritability
  • Memory loss or confusion
  • Soreness of the mouth or tongue
  • Pale skin
  • Digestive issues, such as diarrhea or constipation

Lack of vitamin B12 can result in serious health issues like anemia, nerve damage, and cognitive decline if left untreated.

Symptoms of Iron Deficiency

Another widespread issue is an iron deficiency, particularly among women and children. Iron deficiency symptoms can resemble vitamin B12 deficiency symptoms. Common signs of iron deficiency include the following:

  • Fatigue and weakness
  • Pale skin
  • Shortness of breath
  • Dizziness or lightheadedness
  • Brittle nails
  • Cold hands and feet
  • Headaches
  • Chest pain
  • Rapid heartbeat

Iron deficiency can cause anemia, heart issues, and developmental delays in children if left untreated.

How Iron Deficiency Anemia is Related to Vitamin B12 Deficiency

Due to the fact that both iron and vitamin B12 are necessary for the development of healthy red blood cells, iron deficiency anemia and vitamin B12 deficiency may be connected. Hemoglobin, which carries oxygen in the blood, is made possible by iron. For red blood cells to be produced, vitamin B12 is required. Anemia could result from a lack of either of these nutrients, which would prevent the body from producing enough healthy red blood cells.

Shortness of breath, weakness, and fatigue are all symptoms of anemia. If untreated, it can also harm the heart, brain, and other organs. You should consult your healthcare provider if you think you might have anemia, a vitamin B12 or iron deficiency, or both.

Causes of Vitamin B12 Deficiency

Animal products like meat, fish, poultry, eggs, and dairy contain vitamin B12 naturally. Consequently, those who consume a vegan or vegetarian diet are more likely to become Vitamin B12 deficient. Insufficient intake of vitamin B12 can also result from:

  • Age: As we get older, our bodies become less capable of absorbing Vitamin B12, which causes a deficiency.
  • Gastrointestinal disorders: Some gastrointestinal conditions, like Crohn's disease and celiac disease, can prevent the body from absorbing vitamin B12.
  • Medications: A number of drugs, including metformin, proton pump inhibitors, and antacids, can prevent the absorption of vitamin B12.

Causes of Iron Deficiency

Animal products like meat, fish, and poultry as well as plant-based foods like beans, lentils, and spinach naturally contain iron. A deficiency in iron can, however, result from certain factors interfering with its absorption. Common causes of iron deficiency include the following:

  • Poor diet: A diet low in iron can cause a deficiency. For those who consume a vegan or vegetarian diet, this is especially true.
  • Blood loss: Iron deficiency in women who have heavy menstrual bleeding is more likely to occur. Additionally, a deficiency may result from blood loss from an operation or injury.
  • Pregnancy: To support the growth and development of the fetus, pregnant women need more iron. Premature birth and low birth weight are just two complications that can result from an iron deficiency during pregnancy.
  • Gastrointestinal disorders: Celiac disease and inflammatory bowel disease are two gastrointestinal conditions that can prevent iron from being absorbed.

Diagnosis of Vitamin B12 and Iron Deficiency

Blood tests are frequently used to diagnose vitamin B12 and iron deficiencies by assessing the body's levels of these nutrients. Low blood levels of iron or vitamin B12 may be signs of a deficiency. Additional tests might be required in some circumstances to identify the underlying cause of the deficiency.

It is crucial to remember that many of the signs of iron and vitamin B12 deficiency can also be caused by other illnesses. As a result, it's crucial to seek the advice of a medical expert for a precise diagnosis.

Treatment options for Vitamin B12 and Iron deficiency

The good news is that dietary modifications and supplements can be used to treat both iron and vitamin B12 deficiency. Prescription medicines might also be required in some circumstances.

The most efficient treatment for vitamin B12 deficiency is typically vitamin B12 injections or supplements. Injections are frequently administered once per month, whereas supplements can be taken orally every day. In some circumstances, dietary modifications might also be required to guarantee adequate Vitamin B12 intake.

Iron supplements or dietary changes are two ways to treat iron deficiency. Usually taken orally, iron supplements are available on a doctor's prescription. To ensure adequate intake of iron, dietary changes may occasionally be required. Red meat, poultry, fish, beans, and leafy green vegetables are among the foods high in iron.

Foods rich in Vitamin B12 and Iron

Eating a healthy, balanced diet is one of the best ways to make sure you are getting enough vitamin B12 and iron. These nutrients are present in a wide variety of foods, including:

Foods rich in Vitamin B12

  • Shellfish, such as clams, mussels, and crab
  • Fish, such as salmon, trout, and tuna
  • Meat, such as beef, lamb, and chicken
  • Dairy products, such as milk, cheese, and yogurt
  • Eggs
  • Fortified breakfast cereals

Foods rich in Iron

  • Red meat, such as beef, pork, and lamb
  • Poultry, such as chicken and turkey
  • Seafood, such as clams, oysters, and sardines
  • Beans and lentils
  • Dark leafy greens, such as spinach and kale
  • Fortified breakfast cereals

You should eat foods high in vitamin C, such as citrus fruits, strawberries, and bell peppers, along with foods high in iron because vitamin C can improve the absorption of iron.

Supplements for Vitamin B12 and Iron

Supplements can be a good choice if you can't get enough iron and vitamin B12 from your diet alone. Before beginning any new supplements, you should consult your doctor, though, as taking too much of some nutrients can be harmful.

Tablets, capsules, and injections are just a few of the supplement forms for vitamin B12. It's critical to select a supplement that is suitable for your requirements and to take it as directed.

Tablets, capsules, and liquid forms of iron supplements are additionally offered. Once more, it's crucial to select a supplement that's right for you and to take it as directed.

Prevention of Vitamin B12 and Iron deficiency

To maintain good health, it's critical to avoid iron and vitamin B12 deficiencies. Here are some recommendations to help avoid a deficiency:

  • Consume foods high in iron and vitamin B12 as part of a healthy, balanced diet.
  • You might want to think about taking a vitamin B12 supplement if you eat a vegan or vegetarian diet.
  • Cook with cast iron utensils to raise the iron content of your food.
  • Tea and coffee can hinder the absorption of iron, so avoid drinking them with meals.
  • If you take any medications, discuss them with your healthcare provider because some medications may prevent you from absorbing nutrients.


1. What is the difference between Vitamin 12 and Iron deficiency?

In terms of the symptoms they produce and the bodily processes they carry out, vitamin B12 deficiency and iron deficiency are distinct from one another. Red blood cell synthesis, nervous system health, and DNA synthesis are all supported by vitamin B12 intake. Anemia and neurological issues can result from a vitamin deficiency. The production of hemoglobin, a protein found in red blood cells that transports oxygen throughout the body, however, requires iron. Anemia, which results in weakness, exhaustion, and pale skin, is brought on by a lack of iron.

2. Does Vitamin B12 increase iron levels?

The body's iron levels are not directly raised by vitamin B12. A lack of this vitamin, however, can cause anemia, a condition in which the body lacks enough red blood cells to carry oxygen to the tissues. Anemia caused by an iron deficiency is a common condition because iron is required to make hemoglobin. In order to avoid anemia and make sure your body can produce enough red blood cells, it's critical to address any Vitamin B12 deficiencies.

3. How long does it take to recover from Vitamin B12 deficiency?

The degree of the vitamin B12 deficiency and the recommended course of treatment will determine how long it takes for a person to recover. If the deficiency is mild, it might be treatable by diet or with the aid of an oral supplement. B12 injections may be required in more serious circumstances. Depending on how the person responds to treatment, recovering completely from a vitamin B12 deficiency may take several weeks or months.

4. What causes high B12 and low Iron?

Numerous conditions, such as liver or kidney disease, leukemia, and certain cancers, can result in high blood levels of vitamin B12. In some circumstances, it might be brought on by oversupplementation. Contrarily, low levels of iron can be brought on by a diet low in iron, malabsorption, or blood loss brought on by an injury or menstruation.

5. Can Vitamin B12 deficiency be a sign of cancer?

A lack of vitamin B12 can be a symptom of some cancers, though it is not always a sign of cancer. A lack of this vitamin may be brought on, in part, by leukemia and other blood cancers. The absence of vitamin B12 in the diet or malabsorption, however, can also result in a deficiency.


Two nutrients that are essential for maintaining a healthy body are iron and vitamin B12. Anemia, fatigue, weakness, and other health issues can result from a lack of either of these nutrients.

It's crucial to consume a well-balanced diet that features a variety of foods rich in vitamin B12 and iron if you want to make sure you are getting enough of these nutrients. It is crucial to discuss the best course of treatment with your doctor if you are exhibiting signs of iron or vitamin B12 deficiency.

You can help maintain a healthy body and lower your risk of developing health issues linked to deficiencies by taking steps to ensure you are getting enough of these crucial nutrients.


  1. National Institutes of Health. (2022, March 9). Office of Dietary Supplements - Vitamin B12. ‌
  2. National Institutes of Health. (2022, April 5). Office of Dietary Supplements - Iron.
  3. Mayo Clinic. (2019, October 18). Iron deficiency anemia - Symptoms and causes. Mayo Clinic; Mayo Clinic. ‌


All the content on this blog, including medical opinion and any other health-related information, are solely to provide information only. Any information/statements on this blog are not intended to diagnose, treat, cure or prevent any disease, and should NOT be a substitute for health and medical advice that can be provided by your own physician/medical doctor.  We at Nano Singapore Shop, encourage you to consult a doctor before making any health or diet changes, especially any changes related to a specific diagnosis or condition.